Irritable Bowel Syndrome & Smoking
Smoking: Nicotine on the gastric mucosa.
Nicotine is a naturally occurring substance in tobacco that has a complex effect on many organs and systems in the body.
Pharmacologically, Smoking cigarettes results in a fast absorption of nicotine and subsequent distribution over all tissues. Stimulation of peripheral nicotinic receptors leads to increased catecholamines and noradrenaline, resulting in vasoconstriction, tachycardia and an increased myocardial contraction.
After smoking rectal blood flow diminishes, whereas both gastric acid secretion and motility are enhanced.
IBS & Nicotine
· It is theorized that the nicotine in cigarettes affects the smooth muscle inside the colon. This affect may alter gut motility, which is the rate at which waste moves through the colon, which can cause diarrhea, intestinal cramping and bloating.
· Smoking causes some physiologic effects that could potentially worsen gastroesophageal reflux disease (GERD). It decreases the lower esophageal sphincter pressure and increases the number of reflux episodes. Consequently leading to heartburn and reflux.
So here we have it, Cigarette aggravates most of the major symptoms of IBS.
For a lifestyle modification, why don’ you check your nearest smoking cessation clinic.

Background in Biochemistry and Pharmacology. Main goal is to bring out the best in people.