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Irritable Bowel Syndrome & Smoking

Smoking: Nicotine on the gastric mucosa.

Nicotine is a naturally occurring substance in tobacco that has a complex effect on many organs and systems in the body.
Pharmacologically, Smoking cigarettes results in a fast absorption of nicotine and subsequent distribution over all tissues. Stimulation of peripheral nicotinic receptors leads to increased catecholamines and noradrenaline, resulting in vasoconstriction, tachycardia and an increased myocardial contraction.

After smoking rectal blood flow diminishes, whereas both gastric acid secretion and motility are enhanced.

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